World Congress on Advances in Brain Injury, Disorders and Therapeutics October 21-22, 2019 | Tokyo, Japan

A neurological issue is any disorder of the sensory system. Auxiliary, biochemical or electrical variations from the norm in the mind, spinal line or different nerves can bring about the scope of manifestations. Cases of side effects incorporate loss of motion, muscle shortcoming, poor coordination, loss of sensation, seizures, perplexity, torment and modified levels of awareness. There are numerous perceived neurological issue, some moderately normal, however numerous uncommon. They might be evaluated by neurological examination and contemplated and treated inside the specialties of neurology and clinical neuropsychology

A Brain Injury is an injury that results in trauma to the skull or brain. The terms traumatic brain injury and head injury are often used interchangeably in the medical literature. This broad classification includes neuronal injuries, hemorrhages, vascular injuries, cranial nerve injuries, and subdural hygromas, among many others. These classifications can be further categorized as open (penetrating) or closed head injuries

Traumatic brain injury is a degenerative or congenital nature, but caused by external physical force that may produce a diminished or altered state of consciousness, which results in an impairment of cognitive abilities or physical functioning.The disturbances of cognitive, emotional, and behaviour functioning after TBI may produce permanent impairments.There are 3 different types of traumatic brain injury are folowing Mild traumatic brain injury is a trauma to the head that results in a confused state or a loss of consciousness of less than 30 minutes. Moderate traumatic brain injury is a trauma to the head that results in a loss of consciousness of 30 minutes to 24 hours. Severe traumatic brain injury is a trauma to the head that results in a loss of consciousness of greater than 24 hours

Brain Injury is usually reliably visible as structural abnormalities using techniques such as computed tomography (CT) or conventional magnetic resonance imaging (MRI), more subtle disturbances characteristic of mild TBI are not so easily demonstrated by these imaging modalities. Mild TBI results from the main etiologist of neural contusion and axonal injury, which subsequently results in biochemical, metabolic, and cellular changes that may be responsible for some of the long-term problems seen in patients who develop Postconcussion syndrome (PCS). Since several if not all imaging modalities employed in TBI diagnosis are dependent on structural of functional rearrangement of cellular or extracellular components or assessment of blood-brain barrier (BBB) disruption, it is not surprising that surrogate peripheral or central nervous system (CNS) correlates of CT or MRI have been described.

A stroke occurs when blood supply to the brain is interrupted. The way a stroke affects the brain depends on which part of the brain suffers damage. Brain stem strokes can have complex symptoms, and they can be difficult to diagnose. Brain stem strokes can have complex symptoms, and they can be difficult to diagnose. If a stroke in the brain stem results from a clot, the faster blood flow can be restored in this critical area, the better the chances for recovery. The risk factors for brain stem stroke are the same as for stroke in other areas of the brain: high blood pressure, diabetes, heart disease, atrial fibrillation, and smoking. Like strokes in other areas of the brain, brain stem strokes can be caused by a clot or a hemorrhage. There are also rare causes, as an injury to an artery due to sudden head or neck movements

Neurodegeneration is the progressive loss of structure or function of neurons, including the death of neurons. Many neurodegenerative diseases occur as a result of neurodegenerative processes. Such diseases are incurable, resulting in progressive degeneration and/or death of neuron cells. As research progresses, many similarities appear that relate these diseases to one another on a sub-cellular level. Discovering these similarities offers hope for therapeutic advances that could ameliorate many diseases simultaneously. There are many parallels between different neurodegenerative disorders including atypical protein assemblies as well as induced cell death. Neurodegeneration can be found in many different levels of neuronal circuitry ranging from molecular to systemic.

Alzheimer’s is one of the most common causes of dementia among older adults. Dementia is the loss of cognitive functioning, thinking, remembering, and reasoning and behavioral abilities to such an extent that it interferes with a person daily life and activities. Alzheimer's disease is currently ranked as the sixth leading cause of death in the United States. The causes of dementia can vary, depending on the types of brain changes that may be taking place. Other dementias include Lewy body dementia, frontotemporal disorders, and vascular dementia. It is common for people to have mixed dementia a combination of two or more disorders, at least one of which is dementia. Alzheimer's disease is a chronic neurodegenerative disease that usually starts slowly and worsens over time which is caused by 60–70% of cases of dementia.

The central nervous system is the part of the nervous system consisting of the brain and spinal cord. The central nervous system is so named because it integrates information it receives from, and coordinates and influences the activity of, all parts of the bodies of bilaterally symmetric animals that is. Many consider the retina and the optic nerve as well as the olfactory nerves and olfactory epithelium as parts of the CNS, synapsing directly on brain tissue without intermediate ganglia. The CNS is contained within the dorsal body cavity, with the brain housed in the cranial cavity and the spinal cord in the spinal canal. In vertebrates, the brain is protected by the skull, while the spinal cord is protected by the vertebrae. The brain and spinal cord are both enclosed in the meninges in central nervous systems, the intraneuronal space is filled with a large amount of supporting non-nervous cells called neuroglial cells.

Mental health includes emotional, psychological, and social well-being. It affects how we think, feel, and act. It also helps determine how we handle stress, relate to others, and make choices. Mental health is important at every stage of life, from childhood and adolescence through adulthood. Over the course of your life, if you experience mental health problems, your thinking, mood, and behavior could be affected. Many factors contribute to mental health problems, including Biological factors, such as genes or brain chemistry, Life experiences, such as trauma or abuse, Family history of mental health problems. Mental health refers to our cognitive, behavioral, and emotional wellbeing - it is all about how we think, feel, and behave. The term 'mental health' is sometimes used to mean an absence of a mental disorder

The central nervous system is the part of the nervous system consisting of the brain and spinal cord. The central nervous system is so named because it integrates information it receives from, and coordinates and influences the activity of, all parts of the bodies of bilaterally symmetric animals that is. Many consider the retina and the optic nerve as well as the olfactory nerves and olfactory epithelium as parts of the CNS, synapsing directly on brain tissue without intermediate ganglia. The CNS is contained within the dorsal body cavity, with the brain housed in the cranial cavity and the spinal cord in the spinal canal. In vertebrates, the brain is protected by the skull, while the spinal cord is protected by the vertebrae. The brain and spinal cord are both enclosed in the meninges in central nervous systems, the intraneuronal space is filled with a large amount of supporting non-nervous cells called neuroglial cells. A Neurosurgery is a physician who specializes in the diagnosis and surgical treatment of disorders of the central and peripheral nervous system including congenital anomalies, trauma, tumors, vascular disorders, infections of the brain or spine, stroke, or degenerative diseases of the spine

Clinical trials and also tending of the challenges on CNS and Neurology investigate and by taking a gander at the most lately preclinical what’s more clinical investigations. Clinical trial safety and evaluation, Improvement of clinical trial development ,Biomarkers implication in clinical trial, Clinical trial safety and evaluation ,Current challenges in translational CNS research,Improvement of clinical trial development, New approaches for the design of clinical trials, Case reports related to CNS disorders and Neurology, Remedies for CNS & Neurological Disorders. CNS Bio-markers, a chance to be they genetic traits, biochemical transforms or alterations previously, structural alternately practical features, would be needed on assistance the mixed bag of neurological disorders and identify the progression of these diseases