Brain Injury Biomarkers
Brain Injury is usually reliably visible as structural abnormalities using techniques such as computed tomography (CT) or conventional magnetic resonance imaging (MRI), more subtle disturbances characteristic of mild TBI are not so easily demonstrated by these imaging modalities. Mild TBI results from the main etiologist of neural contusion and axonal injury, which subsequently results in biochemical, metabolic, and cellular changes that may be responsible for some of the long-term problems seen in patients who develop Postconcussion syndrome (PCS). Since several if not all imaging modalities employed in TBI diagnosis are dependent on structural of functional rearrangement of cellular or extracellular components or assessment of blood-brain barrier (BBB) disruption, it is not surprising that surrogate peripheral or central nervous system (CNS) correlates of CT or MRI have been described.
- New Methods in Diagnosis
- Different Diagnosis Procedures
- Early Detection Possibilities
- Patient’s Psychological Changes
- Novel Approaches in Biomarkers
- Normal Brain Aging
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